skinbetter science AlphaRet Overnight Cream Review | SkinSourcer

The Shelf · Skincare So Good We Still Haven’t Found the Dupe

skinbetter science AlphaRet Overnight Cream
No. 02 in Edit 042

skinbetter science AlphaRet Overnight Cream

Moisturizers USA Approx. $145

The patent is visible in the ingredient list, which almost never happens. Ethyl Lactyl Retinoate is a retinoid and a lactic acid bonded into a single molecule rather than mixed in a single jar. Anyone can put a retinol and an acid in one cream. Nobody else can put that ingredient in one.

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Why we like the AlphaRet Overnight Cream

  • One molecule doing what people usually alternate two products to do
  • Ceramide NP, squalane and two peptides in the same formula, so it is also the moisturizer
  • Nothing fragranced in the list, which is rare in this price bracket
Texture
Overnight cream, smooth rather than rich, absorbs without a film
Key ingredients
Ethyl Lactyl Retinoate · Glycolic acid · Niacinamide · Ceramide NP · Palmitoyl tripeptide-1 · Squalane
Fragrance
No fragrance or parfum anywhere in the ingredient list.
Best for
Retinoid users who cannot take the irritation · Reactive skin · Anyone who would rather run one step than three
Works on
Fine lines · Skin texture · Sensitivity
Made in
USA
Where to buy
LAZ Skincare
Price
$145, approximate
Listing checked
2026-08-21

Our verdict on the skinbetter science AlphaRet Overnight Cream

The reason it is hard to buy is the reason it is worth buying. Physician dispensed, and the active is genuinely somebody's property.

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Reviewed 2026-08-21. skinbetter science AlphaRet Overnight Cream appears in Skincare So Good We Still Haven’t Found the Dupe. Every product on The Shelf is listed in the product index.